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Heparan sulfate mediates trastuzumab effect in breast cancer cells

BACKGROUND: Trastuzumab is an antibody widely used in the treatment of breast cancer cases that test positive for the human epidermal growth factor receptor 2 (HER2). Many patients, however, become resistant to this antibody, whose resistance has become a major focus in breast cancer research. But d...

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Detalles Bibliográficos
Autores principales: Suarez, Eloah Rabello, Paredes-Gamero, Edgar Julian, Del Giglio, Auro, dos Santos Tersariol, Ivarne Luis, Nader, Helena Bonciani, Pinhal, Maria Aparecida Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850728/
https://www.ncbi.nlm.nih.gov/pubmed/24083474
http://dx.doi.org/10.1186/1471-2407-13-444