Rationale and design of a randomized trial on the impact of aldosterone antagonism on cardiac structure and function in diabetic cardiomyopathy

Development of a cardiomyopathy in diabetes mellitus is independent of traditional risk factors, with no clinical trials targeting specific therapeutic interventions. Myocardial fibrosis is one of the key mechanisms and aldosterone is a key mediator of myocardial fibrosis. We propose that aldosteron...

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Detalles Bibliográficos
Autores principales: Leung, Melissa, Wong, Vincent W, Heritier, Stephane, Mihailidou, Anastasia S, Leung, Dominic Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850740/
https://www.ncbi.nlm.nih.gov/pubmed/24083804
http://dx.doi.org/10.1186/1475-2840-12-139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850740/
https://www.ncbi.nlm.nih.gov/pubmed/24083804
http://dx.doi.org/10.1186/1475-2840-12-139

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