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Rationale and design of a randomized trial on the impact of aldosterone antagonism on cardiac structure and function in diabetic cardiomyopathy

Development of a cardiomyopathy in diabetes mellitus is independent of traditional risk factors, with no clinical trials targeting specific therapeutic interventions. Myocardial fibrosis is one of the key mechanisms and aldosterone is a key mediator of myocardial fibrosis. We propose that aldosteron...

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Detalles Bibliográficos
Autores principales:	Leung, Melissa, Wong, Vincent W, Heritier, Stephane, Mihailidou, Anastasia S, Leung, Dominic Y
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850740/ https://www.ncbi.nlm.nih.gov/pubmed/24083804 http://dx.doi.org/10.1186/1475-2840-12-139

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