High SIRT1 expression is a negative prognosticator in pancreatic ductal adenocarcinoma

BACKGROUND: Several lines of evidence indicate that Sirt1, a class III histone deacetylase (HDAC) is implicated in the initiation and progression of malignancies and thus gained attraction as druggable target. Since data on the role of Sirt1 in pancreatic ductal adenocarcinoma (PDAC) are sparse, we...

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Detalles Bibliográficos
Autores principales: Stenzinger, Albrecht, Endris, Volker, Klauschen, Frederick, Sinn, Bruno, Lorenz, Katja, Warth, Arne, Goeppert, Benjamin, Ehemann, Volker, Muckenhuber, Alexander, Kamphues, Carsten, Bahra, Marcus, Neuhaus, Peter, Weichert, Wilko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850795/
https://www.ncbi.nlm.nih.gov/pubmed/24088390
http://dx.doi.org/10.1186/1471-2407-13-450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850795/
https://www.ncbi.nlm.nih.gov/pubmed/24088390
http://dx.doi.org/10.1186/1471-2407-13-450

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