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Molecular details of ligand selectivity determinants in a promiscuous β-glucan periplasmic binding protein

BACKGROUND: Members of the periplasmic binding protein (PBP) superfamily utilize a highly conserved inter-domain ligand binding site that adapts to specifically bind a chemically diverse range of ligands. This paradigm of PBP ligand binding specificity was recently altered when the structure of the...

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Detalles Bibliográficos
Autores principales: Munshi, Parthapratim, Stanley, Christopher B, Ghimire-Rijal, Sudipa, Lu, Xun, Myles, Dean A, Cuneo, Matthew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850815/
https://www.ncbi.nlm.nih.gov/pubmed/24090243
http://dx.doi.org/10.1186/1472-6807-13-18