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Biomarkers and Surrogate Endpoints: How and When might They Impact Drug Development?
As the pharmaceutical industry starts developing novel molecules developed based on molecular biology principles and a better understanding of the human genome, it becomes increasingly important to develop early indicators of activity and/or toxicity. Biomarkers are measurements based on molecular p...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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IOS Press
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850863/ https://www.ncbi.nlm.nih.gov/pubmed/12364814 http://dx.doi.org/10.1155/2002/438745 |