The Thyroid Receptor Modulator KB3495 Reduces Atherosclerosis Independently of Total Cholesterol in the Circulation in ApoE Deficient Mice

BACKGROUND: Thyroid hormones (TH) regulate cholesterol metabolism but their use as lipid-lowering drugs is restricted due to negative cardiac effects. TH mimetic compounds modulating TH receptor β (THRβ) have been designed as potential drugs, reducing serum cholesterol levels while avoiding apparent...

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Detalles Bibliográficos
Autores principales: Mörk, Lisa-Mari, Rehnmark, Stefan, Davoodpour, Padideh, Norata, Giuseppe Danilo, Larsson, Lilian, Witt, Michael-Robin, Malm, Johan, Parini, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850901/
https://www.ncbi.nlm.nih.gov/pubmed/24324578
http://dx.doi.org/10.1371/journal.pone.0078534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850901/
https://www.ncbi.nlm.nih.gov/pubmed/24324578
http://dx.doi.org/10.1371/journal.pone.0078534

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