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The proteases HtrA2/Omi and UCH-L1 regulate TNF-induced necroptosis
BACKGROUND: In apoptosis, proteolysis by caspases is the primary mechanism for both initiation and execution of programmed cell death (PCD). In contrast, the impact of proteolysis on the regulation and execution of caspase-independent forms of PCD (programmed necrosis, necroptosis) is only marginall...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850939/ https://www.ncbi.nlm.nih.gov/pubmed/24090154 http://dx.doi.org/10.1186/1478-811X-11-76 |