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Non-overlapping activities of ADF and cofilin-1 during the migration of metastatic breast tumor cells

BACKGROUND: ADF/cofilin proteins are key modulators of actin dynamics in metastasis and invasion of cancer cells. Here we focused on the roles of ADF and cofilin-1 individually in the development of polarized migration of rat mammary adenocarcinoma (MTLn3) cells, which express nearly equal amounts o...

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Detalles Bibliográficos
Autores principales: Tahtamouni, Lubna H, Shaw, Alisa E, Hasan, Maram H, Yasin, Salem R, Bamburg, James R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850953/
https://www.ncbi.nlm.nih.gov/pubmed/24093776
http://dx.doi.org/10.1186/1471-2121-14-45