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Genetic background modulates phenotypes of serotonin transporter Ala56 knock-in mice

BACKGROUND: Previously, we identified multiple, rare serotonin (5-HT) transporter (SERT) variants in children with autism spectrum disorder (ASD). Although in our study the SERT Ala56 variant was over-transmitted to ASD probands, it was also seen in some unaffected individuals, suggesting that assoc...

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Detalles Bibliográficos
Autores principales: Kerr, Travis M, Muller, Christopher L, Miah, Mahfuzur, Jetter, Christopher S, Pfeiffer, Rita, Shah, Charisma, Baganz, Nicole, Anderson, George M, Crawley, Jacqueline N, Sutcliffe, James S, Blakely, Randy D, Veenstra-VanderWeele, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851031/
https://www.ncbi.nlm.nih.gov/pubmed/24083388
http://dx.doi.org/10.1186/2040-2392-4-35