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Loss of Imprinting of IGF2 as an Epigenetic Marker for the Risk of Human Cancer
IGF2 is the first gene discovered to be imprinted and expressed exclusively from the paternal allele in both human and mouse. IGF2 is also the first imprinted gene displaying loss of imprinting (LOI) or aberrant imprinting in human cancers. Evidently, LOI or reactivation of the maternal allele of IG...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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IOS Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851053/ https://www.ncbi.nlm.nih.gov/pubmed/17325430 http://dx.doi.org/10.1155/2007/363464 |