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Cancer Diagnosis, Risk Assessment and Prediction of Therapeutic Response by Means of DNA Methylation Markers

Epigenetic alterations are heritable changes in gene expression without an accompanying change in primary DNA sequence. Two major mechanisms that cause epigenetic changes are post-translational histone modifications and DNA methylation at cytosine bases within a CpG dinucleotide. Epigenetic defects...

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Detalles Bibliográficos
Autores principales: Fiegl, Heidi, Elmasry, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851084/
https://www.ncbi.nlm.nih.gov/pubmed/17325428
http://dx.doi.org/10.1155/2007/293138