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Microarray and RNAi Analysis of P450s in Anopheles gambiae Male and Female Steroidogenic Tissues: CYP307A1 Is Required for Ecdysteroid Synthesis

In insects, the steroid hormone 20-hydroxyecdysone (20E) coordinates major developmental transitions. While the first and the final steps of 20E biosynthesis are characterized, the pathway from 7-dehydrocholesterol to 5β-ketodiol, commonly referred as the “black box”, remains hypothetical and whethe...

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Detalles Bibliográficos
Autores principales: Pondeville, Emilie, David, Jean-Philippe, Guittard, Emilie, Maria, Annick, Jacques, Jean-Claude, Ranson, Hilary, Bourgouin, Catherine, Dauphin-Villemant, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851169/
https://www.ncbi.nlm.nih.gov/pubmed/24324583
http://dx.doi.org/10.1371/journal.pone.0079861