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Up-regulation of alpha-smooth muscle actin in cardiomyocytes from non-hypertrophic and non-failing transgenic mouse hearts expressing N-terminal truncated cardiac troponin I()

We previously reported that a restrictive N-terminal truncation of cardiac troponin I (cTnI-ND) is up-regulated in the heart in adaptation to hemodynamic stresses. Over-expression of cTnI-ND in the hearts of transgenic mice revealed functional benefits such as increased relaxation and myocardial com...

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Detalles Bibliográficos
Autores principales: Kern, Stephanie, Feng, Han-Zhong, Wei, Hongguang, Cala, Steven, Jin, J.-P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851183/
https://www.ncbi.nlm.nih.gov/pubmed/24319652
http://dx.doi.org/10.1016/j.fob.2013.11.002