Circadian transcriptome analysis in human fibroblasts from Hunter syndrome and impact of iduronate-2-sulfatase treatment

BACKGROUND: Hunter syndrome (HS) is a lysosomal storage disease caused by iduronate-2-sulfatase (IDS) deficiency and loss of ability to break down and recycle the glycosaminoglycans, heparan and dermatan sulfate, leading to impairment of cellular processes and cell death. Cell activities and functio...

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Detalles Bibliográficos
Autores principales: Mazzoccoli, Gianluigi, Tomanin, Rosella, Mazza, Tommaso, D’Avanzo, Francesca, Salvalaio, Marika, Rigon, Laura, Zanetti, Alessandra, Pazienza, Valerio, Francavilla, Massimo, Giuliani, Francesco, Vinciguerra, Manlio, Scarpa, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851237/
https://www.ncbi.nlm.nih.gov/pubmed/24083598
http://dx.doi.org/10.1186/1755-8794-6-37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851237/
https://www.ncbi.nlm.nih.gov/pubmed/24083598
http://dx.doi.org/10.1186/1755-8794-6-37

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