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Differential reconstructed gene interaction networks for deriving toxicity threshold in chemical risk assessment
BACKGROUND: Pathway alterations reflected as changes in gene expression regulation and gene interaction can result from cellular exposure to toxicants. Such information is often used to elucidate toxicological modes of action. From a risk assessment perspective, alterations in biological pathways ar...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851258/ https://www.ncbi.nlm.nih.gov/pubmed/24268022 http://dx.doi.org/10.1186/1471-2105-14-S14-S3 |