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Differential reconstructed gene interaction networks for deriving toxicity threshold in chemical risk assessment

BACKGROUND: Pathway alterations reflected as changes in gene expression regulation and gene interaction can result from cellular exposure to toxicants. Such information is often used to elucidate toxicological modes of action. From a risk assessment perspective, alterations in biological pathways ar...

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Detalles Bibliográficos
Autores principales:	Yang, Yi, Maxwell, Andrew, Zhang, Xiaowei, Wang, Nan, Perkins, Edward J, Zhang, Chaoyang, Gong, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851258/ https://www.ncbi.nlm.nih.gov/pubmed/24268022 http://dx.doi.org/10.1186/1471-2105-14-S14-S3

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