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Glycation Accelerates Fibrillization of the Amyloidogenic W7FW14F Apomyoglobin

Neurodegenerative diseases are associated with misfolding and deposition of specific proteins, either intra or extracellularly in the nervous system. Advanced glycation end products (AGEs) originate from different molecular species that become glycated after exposure to sugars. Several proteins impl...

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Detalles Bibliográficos
Autores principales: Iannuzzi, Clara, Maritato, Rosa, Irace, Gaetano, Sirangelo, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851467/
https://www.ncbi.nlm.nih.gov/pubmed/24324625
http://dx.doi.org/10.1371/journal.pone.0080768