Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia

BACKGROUND: The MRE11, RAD50, and NBN genes encode proteins of the MRE11-RAD50-NBN (MRN) complex involved in cellular response to DNA damage and the maintenance of genome stability. In our previous study we showed that the germline p.I171V mutation in NBN may be considered as a risk factor in the de...

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Detalles Bibliográficos
Autores principales: Mosor, Maria, Ziółkowska-Suchanek, Iwona, Nowicka, Karina, Dzikiewicz-Krawczyk, Agnieszka, Januszkiewicz–Lewandowska, Danuta, Nowak, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851537/
https://www.ncbi.nlm.nih.gov/pubmed/24093751
http://dx.doi.org/10.1186/1471-2407-13-457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851537/
https://www.ncbi.nlm.nih.gov/pubmed/24093751
http://dx.doi.org/10.1186/1471-2407-13-457

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