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Antisense oligonucleotide suppression of human IGF-1R inhibits the growth and survival of in vitro cultured epithelial ovarian cancer cells

BACKGROUND: Preclinical evaluation of the anti-neoplastic activity of antisense oligonucleotide (AS) suppression of human insulin-like growth factor I receptor (IGF-IR) in human epithelial ovarian cancer (EOC). METHODS: Ovarian cancer cells from 36 patients with EOC were investigated under serum-fre...

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Detalles Bibliográficos
Autores principales: Tang, Jie, Li, Junjun, Zeng, Guqing, Tang, Yanxiang, Tian, Wenfang, He, Jie, York, J Philippe, Xia, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851551/
https://www.ncbi.nlm.nih.gov/pubmed/24103397
http://dx.doi.org/10.1186/1757-2215-6-71