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The Gly482Ser Missense Mutation of the Peroxisome Proliferator-Activated Receptor γ Coactivator-1α (PGC-1α) Gene Associates with Reduced Insulin Sensitivity in Normal and Glucose-Intolerant Obese Subjects

Among the putative candidate genes for insulin resistance, the peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) is a transcriptional coactivator of PPARγ and α, regulating a wide range of processes involved in energy production and utilization, such as thermogenesis, liver glucon...

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Detalles Bibliográficos
Autores principales: Fanelli, Marzia, Filippi, Emanuela, Sentinelli, Federica, Romeo, Stefano, Fallarino, Mara, Buzzetti, Raffaella, Leonetti, Frida, Baroni, Marco Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851614/
https://www.ncbi.nlm.nih.gov/pubmed/16403952
http://dx.doi.org/10.1155/2005/576748