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MUC Gene Abnormalities in Sporadic and Hereditary Mucinous Colon Cancers with Microsatellite Instability

Aim of this study was verifying whether mucin producing colon cancers (CRCs) could develop through a molecular pathway involving microsatellite instability (MSI) and MUC gene alterations. Out of 49 CRCs expressing variable amounts of mucin, 22 (44.9%) were MSI-H and 5 (10.2%) were MSI-L. MUC genes w...

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Detalles Bibliográficos
Autores principales: Pastrello, Chiara, Santarosa, Manuela, Fornasarig, Mara, Sigon, Roberto, Perin, Tiziana, Giannini, Giuseppe, Boiocchi, Mauro, Viel, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851629/
https://www.ncbi.nlm.nih.gov/pubmed/16276005
http://dx.doi.org/10.1155/2005/370908