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QT Interval Prolongation as a Biomarker for Torsades de Pointes and Sudden Death in Drug Development
Prolongation of the QT interval on the surface 12-lead electrocardiogram is widely accepted as a biomarker for the potential of a drug to produce torsades de pointes and/or sudden death. Detection of drug-induced prolongation of the QT interval in animals and man is frequently confounded by extrinsi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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IOS Press
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851643/ https://www.ncbi.nlm.nih.gov/pubmed/12364811 http://dx.doi.org/10.1155/2002/482953 |