Developmental arrest of Drosophila survival motor neuron (Smn) mutants accounts for differences in expression of minor intron-containing genes

Reduced levels of survival motor neuron (SMN) protein lead to a neuromuscular disease called spinal muscular atrophy (SMA). Animal models of SMA recapitulate many aspects of the human disease, including locomotion and viability defects, but have thus far failed to uncover the causative link between...

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Detalles Bibliográficos
Autores principales: Garcia, Eric L., Lu, Zhipeng, Meers, Michael P., Praveen, Kavita, Matera, A. Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851718/
https://www.ncbi.nlm.nih.gov/pubmed/24006466
http://dx.doi.org/10.1261/rna.038919.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851718/
https://www.ncbi.nlm.nih.gov/pubmed/24006466
http://dx.doi.org/10.1261/rna.038919.113

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