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ADAR1 regulates ARHGAP26 gene expression through RNA editing by disrupting miR-30b-3p and miR-573 binding

Rho GTPase activating protein 26 (ARHGAP26) is a negative regulator of the Rho family that converts the small G proteins RhoA and Cdc42 to their inactive GDP-bound forms. It is essential for the CLIC/GEEC endocytic pathway, cell spreading, and muscle development. The present study shows that ARHGAP2...

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Detalles Bibliográficos
Autores principales: Wang, Qiong, Hui, Haipeng, Guo, Zhendong, Zhang, Weina, Hu, Yaou, He, Tao, Tai, Yanhong, Peng, Peng, Wang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851720/
https://www.ncbi.nlm.nih.gov/pubmed/24067935
http://dx.doi.org/10.1261/rna.041533.113