Deep mutational scanning of an RRM domain of the Saccharomyces cerevisiae poly(A)-binding protein

The RNA recognition motif (RRM) is the most common RNA-binding domain in eukaryotes. Differences in RRM sequences dictate, in part, both RNA and protein-binding specificities and affinities. We used a deep mutational scanning approach to study the sequence-function relationship of the RRM2 domain of...

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Detalles Bibliográficos
Autores principales: Melamed, Daniel, Young, David L., Gamble, Caitlin E., Miller, Christina R., Fields, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851721/
https://www.ncbi.nlm.nih.gov/pubmed/24064791
http://dx.doi.org/10.1261/rna.040709.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851721/
https://www.ncbi.nlm.nih.gov/pubmed/24064791
http://dx.doi.org/10.1261/rna.040709.113

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