The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly

Argonaute2 (Ago2) protein and associated microRNAs (miRNAs) or small interfering RNAs (siRNAs) form the RNA-induced silencing complex (RISC) for target messenger RNA cleavage and post-transcriptional gene silencing. Although Ago2 is essential for RISC activity, the mechanism of RISC assembly is not...

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Detalles Bibliográficos
Autores principales: Martinez, Natalia J., Chang, Hao-Ming, Borrajo, Jacob de Riba, Gregory, Richard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851725/
https://www.ncbi.nlm.nih.gov/pubmed/24049110
http://dx.doi.org/10.1261/rna.040790.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851725/
https://www.ncbi.nlm.nih.gov/pubmed/24049110
http://dx.doi.org/10.1261/rna.040790.113

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