Disposition and Metabolism of Setipiprant, a Selective Oral CRTH2 Antagonist, in Humans

BACKGROUND: Setipiprant, a tetrahydropyridoindole derivative, is a CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper [Th]-2 cells) antagonist that has the potential to be effective in the treatment of patients with diseases with an allergic etiology, such as allergic rhinitis...

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Detalles Bibliográficos
Autores principales: Hoch, Matthias, Wank, Janine, Kluge, Ina, Wagner-Redeker, Winfried, Dingemanse, Jasper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851755/
https://www.ncbi.nlm.nih.gov/pubmed/24214422
http://dx.doi.org/10.1007/s40268-013-0031-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851755/
https://www.ncbi.nlm.nih.gov/pubmed/24214422
http://dx.doi.org/10.1007/s40268-013-0031-7

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