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IGF binding protein 2 is a cell-autonomous factor supporting survival and migration of acute leukemia cells
BACKGROUND: The role of IGF binding protein 2 (IGFBP2) in cancer development is intriguing. Previously we identified IGFBP2 as an extrinsic factor that supports the activity of hematopoietic stem cells (HSCs). METHODS AND RESULTS: Here we investigated the role of IGFBP2 in in human leukemia cells an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851819/ https://www.ncbi.nlm.nih.gov/pubmed/24191913 http://dx.doi.org/10.1186/1756-8722-6-72 |