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IGF binding protein 2 is a cell-autonomous factor supporting survival and migration of acute leukemia cells

BACKGROUND: The role of IGF binding protein 2 (IGFBP2) in cancer development is intriguing. Previously we identified IGFBP2 as an extrinsic factor that supports the activity of hematopoietic stem cells (HSCs). METHODS AND RESULTS: Here we investigated the role of IGFBP2 in in human leukemia cells an...

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Detalles Bibliográficos
Autores principales:	Chen, Xiaoli, Zheng, Junke, Zou, Yizhou, Song, Chun, Hu, Xuemei, Zhang, Cheng Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851819/ https://www.ncbi.nlm.nih.gov/pubmed/24191913 http://dx.doi.org/10.1186/1756-8722-6-72

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