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Aberrantly methylated genes in human papillary thyroid cancer and their association with BRAF/RAS mutation
Cancer arises through accumulation of epigenetic and genetic alteration. Aberrant promoter methylation is a common epigenetic mechanism of gene silencing in cancer cells. We here performed genome-wide analysis of DNA methylation of promoter regions by Infinium HumanMethylation27 BeadChip, using 14 c...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851831/ https://www.ncbi.nlm.nih.gov/pubmed/24367375 http://dx.doi.org/10.3389/fgene.2013.00271 |