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Sorting genomes with rearrangements and segmental duplications through trajectory graphs

We study the problem of sorting genomes under an evolutionary model that includes genomic rearrangements and segmental duplications. We propose an iterative algorithm to improve any initial evolutionary trajectory between two genomes in terms of parsimony. Our algorithm is based on a new graphical m...

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Detalles Bibliográficos
Autores principales: Shao, Mingfu, Lin, Yu, Moret, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851842/
https://www.ncbi.nlm.nih.gov/pubmed/24564345
http://dx.doi.org/10.1186/1471-2105-14-S15-S9