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The effects of different doses of estradiol (E2) on cerebral ischemia in an in vitro model of oxygen and glucose deprivation and reperfusion and in a rat model of middle carotid artery occlusion

BACKGROUND: Because neuroprotective effects of estrogen remain controversial, we aimed to investigate the effect of different doses of estradiol (E2) on cerebral ischemia using both in vivo and in vitro experiments. RESULTS: PC12 cells were cultured at physiological (10 nM and 20 nM) or pharmacologi...

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Detalles Bibliográficos
Autores principales: Ma, Yu-Long, Qin, Pei, Li, Yan, Shen, Lan, Wang, Shi-Quan, Dong, Hai-Long, Hou, Wu-Gang, Xiong, Li-Ze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851874/
https://www.ncbi.nlm.nih.gov/pubmed/24106772
http://dx.doi.org/10.1186/1471-2202-14-118