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Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control

Stem cell-based disease modeling presents unique opportunities for mechanistic elucidation and therapeutic targeting. The stable induction of fate-specific differentiation is an essential prerequisite for stem cell-based strategy. Bone morphogenetic protein 2 (BMP-2) initiates receptor-regulated Sma...

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Detalles Bibliográficos
Autores principales: Honda, Yoshitomo, Ding, Xianting, Mussano, Federico, Wiberg, Akira, Ho, Chih-ming, Nishimura, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851880/
https://www.ncbi.nlm.nih.gov/pubmed/24305548
http://dx.doi.org/10.1038/srep03420