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Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control
Stem cell-based disease modeling presents unique opportunities for mechanistic elucidation and therapeutic targeting. The stable induction of fate-specific differentiation is an essential prerequisite for stem cell-based strategy. Bone morphogenetic protein 2 (BMP-2) initiates receptor-regulated Sma...
Autores principales: | Honda, Yoshitomo, Ding, Xianting, Mussano, Federico, Wiberg, Akira, Ho, Chih-ming, Nishimura, Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851880/ https://www.ncbi.nlm.nih.gov/pubmed/24305548 http://dx.doi.org/10.1038/srep03420 |
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