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Identification of mutated core cancer modules by integrating somatic mutation, copy number variation, and gene expression data

MOTIVATION: Understanding the molecular mechanisms underlying cancer is an important step for the effective diagnosis and treatment of cancer patients. With the huge volume of data from the large-scale cancer genomics projects, an open challenge is to distinguish driver mutations, pathways, and gene...

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Detalles Bibliográficos
Autores principales: Zhang, Junhua, Zhang, Shihua, Wang, Yong, Zhang, Xiang-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851989/
https://www.ncbi.nlm.nih.gov/pubmed/24565034
http://dx.doi.org/10.1186/1752-0509-7-S2-S4