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Identification of mutated core cancer modules by integrating somatic mutation, copy number variation, and gene expression data
MOTIVATION: Understanding the molecular mechanisms underlying cancer is an important step for the effective diagnosis and treatment of cancer patients. With the huge volume of data from the large-scale cancer genomics projects, an open challenge is to distinguish driver mutations, pathways, and gene...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851989/ https://www.ncbi.nlm.nih.gov/pubmed/24565034 http://dx.doi.org/10.1186/1752-0509-7-S2-S4 |