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Asymmetry in Erythroid-Myeloid Differentiation Switch and the Role of Timing in a Binary Cell-Fate Decision

GATA1-PU.1 genetic switch is a paradigmatic genetic switch that governs the differentiation of progenitor cells into two different fates, erythroid and myeloid fates. In terms of dynamical model representation of these fates or lineages corresponds to stable attractor and choosing between the attrac...

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Detalles Bibliográficos
Autores principales: Alagha, Afnan, Zaikin, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851994/
https://www.ncbi.nlm.nih.gov/pubmed/24367366
http://dx.doi.org/10.3389/fimmu.2013.00426