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Crystal Structures of the Human G3BP1 NTF2-Like Domain Visualize FxFG Nup Repeat Specificity

Ras GTPase Activating Protein SH3 Domain Binding Protein (G3BP) is a potential anti-cancer drug target implicated in several cellular functions. We have used protein crystallography to solve crystal structures of the human G3BP1 NTF2-like domain both alone and in complex with an FxFG Nup repeat pept...

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Detalles Bibliográficos
Autores principales: Vognsen, Tina, Møller, Ingvar Runár, Kristensen, Ole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852005/
https://www.ncbi.nlm.nih.gov/pubmed/24324649
http://dx.doi.org/10.1371/journal.pone.0080947