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Combining in silico prediction and ribosome profiling in a genome-wide search for novel putatively coding sORFs

BACKGROUND: It was long assumed that proteins are at least 100 amino acids (AAs) long. Moreover, the detection of short translation products (e.g. coded from small Open Reading Frames, sORFs) is very difficult as the short length makes it hard to distinguish true coding ORFs from ORFs occurring by c...

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Detalles Bibliográficos
Autores principales: Crappé, Jeroen, Van Criekinge, Wim, Trooskens, Geert, Hayakawa, Eisuke, Luyten, Walter, Baggerman, Geert, Menschaert, Gerben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852105/
https://www.ncbi.nlm.nih.gov/pubmed/24059539
http://dx.doi.org/10.1186/1471-2164-14-648