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Combining in silico prediction and ribosome profiling in a genome-wide search for novel putatively coding sORFs
BACKGROUND: It was long assumed that proteins are at least 100 amino acids (AAs) long. Moreover, the detection of short translation products (e.g. coded from small Open Reading Frames, sORFs) is very difficult as the short length makes it hard to distinguish true coding ORFs from ORFs occurring by c...
Autores principales: | Crappé, Jeroen, Van Criekinge, Wim, Trooskens, Geert, Hayakawa, Eisuke, Luyten, Walter, Baggerman, Geert, Menschaert, Gerben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852105/ https://www.ncbi.nlm.nih.gov/pubmed/24059539 http://dx.doi.org/10.1186/1471-2164-14-648 |
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