Radioprotective effects of oral 17-dimethylaminoethylamino-17-demethoxygeldanamycin in mice: bone marrow and small intestine

BACKGROUND: Our previous research demonstrated that one subcutaneous injection of 17-Dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) 24 hours (h) before irradiation (8.75 Gy) increased mouse survival by 75%. However, the protective mechanism of 17-DMAG is currently unknown. The present st...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Xinyue, Nurmemet, Dilber, Bolduc, David L, Elliott, Thomas B, Kiang, Juliann G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852109/
https://www.ncbi.nlm.nih.gov/pubmed/24499553
http://dx.doi.org/10.1186/2045-3701-3-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852109/
https://www.ncbi.nlm.nih.gov/pubmed/24499553
http://dx.doi.org/10.1186/2045-3701-3-36

Ejemplares similares