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MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3

BACKGROUND: microRNA 21 (miR-21) has been demonstrated to be significantly elevated in many types of cancers, including the hepatocellular carcinoma (HCC). In the present study, we investigated the role of miR-21 in HCC by identifying its novel targets, as well as its underlying molecular mechanism....

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Detalles Bibliográficos
Autores principales: Xu, Guangxian, Zhang, Yilin, Wei, Jun, Jia, Wei, Ge, Zhaohui, Zhang, Zhaobo, Liu, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852118/
https://www.ncbi.nlm.nih.gov/pubmed/24112539
http://dx.doi.org/10.1186/1471-2407-13-469