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MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3
BACKGROUND: microRNA 21 (miR-21) has been demonstrated to be significantly elevated in many types of cancers, including the hepatocellular carcinoma (HCC). In the present study, we investigated the role of miR-21 in HCC by identifying its novel targets, as well as its underlying molecular mechanism....
Autores principales: | Xu, Guangxian, Zhang, Yilin, Wei, Jun, Jia, Wei, Ge, Zhaohui, Zhang, Zhaobo, Liu, Xiaoming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852118/ https://www.ncbi.nlm.nih.gov/pubmed/24112539 http://dx.doi.org/10.1186/1471-2407-13-469 |
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