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A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat RNA

Fluorescent imaging of RNA in living cells is a technically challenging problem in cell biology. One strategy for genetically encoding fluorescent RNAs is to express them as fusions with ‘RNA mimics of GFP’. These are short aptamer tags that exhibit fluorescence upon binding otherwise nonfluorescent...

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Detalles Bibliográficos
Autores principales: Strack, Rita L., Disney, Matthew D., Jaffrey, Samie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852148/
https://www.ncbi.nlm.nih.gov/pubmed/24162923
http://dx.doi.org/10.1038/nmeth.2701