PKPD Modeling of VEGF, sVEGFR-2, sVEGFR-3, and sKIT as Predictors of Tumor Dynamics and Overall Survival Following Sunitinib Treatment in GIST

The predictive value of longitudinal biomarker data (vascular endothelial growth factor (VEGF), soluble VEGF receptor (sVEGFR)-2, sVEGFR-3, and soluble stem cell factor receptor (sKIT)) for tumor response and survival was assessed based on data from 303 patients with imatinib-resistant gastrointesti...

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Detalles Bibliográficos
Autores principales: Hansson, E K, Amantea, M A, Westwood, P, Milligan, P A, Houk, B E, French, J, Karlsson, M O, Friberg, L E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852160/
https://www.ncbi.nlm.nih.gov/pubmed/24257372
http://dx.doi.org/10.1038/psp.2013.61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852160/
https://www.ncbi.nlm.nih.gov/pubmed/24257372
http://dx.doi.org/10.1038/psp.2013.61

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