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PKPD Modeling of VEGF, sVEGFR-2, sVEGFR-3, and sKIT as Predictors of Tumor Dynamics and Overall Survival Following Sunitinib Treatment in GIST
The predictive value of longitudinal biomarker data (vascular endothelial growth factor (VEGF), soluble VEGF receptor (sVEGFR)-2, sVEGFR-3, and soluble stem cell factor receptor (sKIT)) for tumor response and survival was assessed based on data from 303 patients with imatinib-resistant gastrointesti...
Autores principales: | Hansson, E K, Amantea, M A, Westwood, P, Milligan, P A, Houk, B E, French, J, Karlsson, M O, Friberg, L E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852160/ https://www.ncbi.nlm.nih.gov/pubmed/24257372 http://dx.doi.org/10.1038/psp.2013.61 |
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