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Histone deacetylases and their role in motor neuron degeneration

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by the progressive loss of motor neurons. The cause of this selective neuronal death is unknown, but transcriptional dysregulation is recently emerging as an important factor. The physical substrate for the regul...

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Detalles Bibliográficos
Autores principales: Lazo-Gómez, Rafael, Ramírez-Jarquín, Uri N., Tovar-y-Romo, Luis B., Tapia, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852234/
https://www.ncbi.nlm.nih.gov/pubmed/24367290
http://dx.doi.org/10.3389/fncel.2013.00243