Systematic Construction of Kinetic Models from Genome-Scale Metabolic Networks

The quantitative effects of environmental and genetic perturbations on metabolism can be studied in silico using kinetic models. We present a strategy for large-scale model construction based on a logical layering of data such as reaction fluxes, metabolite concentrations, and kinetic constants. The...

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Detalles Bibliográficos
Autores principales: Stanford, Natalie J., Lubitz, Timo, Smallbone, Kieran, Klipp, Edda, Mendes, Pedro, Liebermeister, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852239/
https://www.ncbi.nlm.nih.gov/pubmed/24324546
http://dx.doi.org/10.1371/journal.pone.0079195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852239/
https://www.ncbi.nlm.nih.gov/pubmed/24324546
http://dx.doi.org/10.1371/journal.pone.0079195

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