Inclusion of CYP3A5 genotyping in a nonparametric population model improves dosing of tacrolimus early after transplantation

Following organ engraftment, initial dosing of tacrolimus is based on recipient weight and adjusted by measured C(0) concentrations. The bioavailability and elimination of tacrolimus are affected by the patients CYP3A5 genotype. Prospective data of the clinical advantage of knowing patient's CY...

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Detalles Bibliográficos
Autores principales: Åsberg, Anders, Midtvedt, Karsten, van Guilder, Mike, Størset, Elisabet, Bremer, Sara, Bergan, Stein, Jelliffe, Roger, Hartmann, Anders, Neely, Michael N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852421/
https://www.ncbi.nlm.nih.gov/pubmed/24118301
http://dx.doi.org/10.1111/tri.12194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852421/
https://www.ncbi.nlm.nih.gov/pubmed/24118301
http://dx.doi.org/10.1111/tri.12194

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